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AssigneeKobiolabs, Inc.
InventorsWoo Ri Ko, June Chul Lee, Tae-Wook Nam, Gwang Pyo Ko, Hyun Ju You, So Yon Yoon, Seok Cheon Song
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A strain of Lactobacillus crispatus KBL693 and the use thereof are disclosed. The strain of Lactobacillus crispatus KBL693 (Accession No. KCTC 13519BP) attenuates allergic reactions of cells, significantly improves symptoms of atopic dermatitis, and exhibits anti-inflammatory and anti-fungal effects. Thus, the single strain alone can achieve all the purposes of alleviating atopic dermatitis and other allergic diseases and improving inflammatory diseases and autoimmune diseases, thereby finding advantageous applications as a probiotic substance. In addition, the strain, based on the anti-fungal activity thereof, can be advantageously utilized in a skin external preparation against various skin diseases caused by fungi, and in a cosmetic composition and a functional patch for alleviating sensitive skin.
A method for alleviation of allergic disease, alleviation of inflammatory disease or autoimmune disease, comprising administering at least one selected from the group consisting of strain of a Lactobacillus crispatus KBL693 with Accession No. KCTC 13519BP, culture of said strain and lysate of said strain to a subject in need thereof.
A method for treating or preventing allergic disease, inflammatory disease or autoimmune disease, comprising administering at least one selected from the group consisting of strain of a Lactobacillus crispatus KBL693 with Accession No. KCTC 13519BP, culture of said strain and lysate of said strain to a subject in need thereof.
A method for improving cutaneous allergy, skin urticaria, atopic dermatitis, psoriasis, mycotic infection or eczema, comprising administering a cosmetic composition to a subject in need thereof, wherein said cosmetic composition comprises at least one selected from the group consisting of strain of a Lactobacillus crispatus KBL693 with Accession No. KCTC 13519BP, culture of said strain and lysate of said strain.
Dependencies are inferred from the claim text.