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US 11,633,436 B2Granted
Cholesterol reducing compositions and methods of use thereof
AssigneesThe Broad Institute, Inc., The General Hospital Corporation, President and Fellows of Harvard College
InventorsDouglas Kenny, Hera Vlamakis, Ramnik Xavier, Emily Balskus, Damian Plichta
Life of this patent
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Abstract
Microbes expressing cholesterol oxidoreductase (COR) proteins, methods of engineering the microbes expressing COR proteins, compositions and methods of using the microbes are provided.
Claims24
A non-naturally occurring microbe engineered to express one or more cholesterol oxidoreductase (COR) proteins or a homolog thereof, wherein the one or more COR proteins or homologs thereof is selected from one or more sequences in Table 1 or Table 2.
Dependencies are inferred from the claim text.