Topical kits and compositions and use thereof
AssigneeTechnion Research & Development Foundation Limited
InventorsBoaz Mizrahi, Maayan Lufton
Life of this patent
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Abstract
Kits and composition comprising: (i) a thermo-responsive hydrogel characterized by a viscosity suitable for hardening after administration on a subject's skin; (ii) a bacterial growth medium; and optionally, (iii) a population of non-pathogenic viable bacteria, are provided. Methods for topically delivering a therapeutic or cosmeceutical agent such as for inhibiting or reducing growth of microorganisms on a subject's skin are further provided.
Claims12
A kit comprising:
- (i) a material characterized by a viscosity that is less than about 1 Pa under a first stimulus, and a viscosity that is higher than about 100 Pa under a second stimulus;
- (ii) a bacterial growth medium;
- and
- (iii) a population of non-pathogenic viable bacteria, wherein said first stimulus comprises a temperature below 35° C., and said second stimulus comprises a temperature above 36° C.;
- and wherein said material is characterized by a gelation time between 30 sec to 15 min.
A kit comprising a material characterized by a viscosity that is less than about 1 Pa under a first stimulus, and a viscosity that is higher than about 100 Pa under a second stimulus;
- and a population of non-pathogenic viable bacteria, wherein said first stimulus comprises a temperature below 35° C., and said second stimulus comprises a temperature above 36° C.;
- wherein said material is characterized by a gelation time between 30 sec to 15 min;
- wherein said material is a hydrogel comprising a polymer and a bacterial growth medium;
- and wherein the non-pathogenic viable bacteria inhibit growth of pathogenic-bacteria, yeast, fungus or virus.
Dependencies are inferred from the claim text.