US 11,633,433 B2 · Anti-bacterial composition against TH1 cell-inducing bacteria

Abstract

With the aim of proving an antibacterial composition against oral bacteria and the like capable of inducing Th1 cell proliferation or activation in an intestinal tract, the present inventors have found out that bacteria that suppress colonization and the like of the oral bacteria and the like in the intestinal tract are present in an intestinal microbiota. Moreover, the present inventors have succeeded in isolating intestinal bacteria that suppress intestinal colonization and the like of oral bacteria and the like.

An antibacterial composition against a bacterium capable of inducing Th1 cell proliferation or activation in an intestinal tract, wherein said antibacterial composition comprises

(1) a bacterium having a DNA comprising a base sequence at least 90% identical to SEQ ID NO:
69,
(2) a bacterium having a DNA comprising a base sequence at least 90% identical to SEQ ID NO:
70,
(3) a bacterium having a DNA comprising a base sequence at least 90% identical to SEQ ID NO:
71,
(4) a bacterium having a DNA comprising a base sequence at least 90% identical to SEQ ID NO:
72,
(5) a bacterium having a DNA comprising a base sequence at least 90% identical to SEQ ID NO:
73,
(6) a bacterium having a DNA comprising a base sequence at least 90% identical to SEQ ID NO:
74,
(7) a bacterium having a DNA comprising a base sequence at least 90% identical to SEQ ID NO:
75,
(8) a bacterium having a DNA comprising a base sequence at least 90% identical to SEQ ID NO:
76,
(9) a bacterium having a DNA comprising a base sequence at least 90% identical to SEQ ID NO:
77,
(10) a bacterium having a DNA comprising a base sequence at least 90% identical to SEQ ID NO:
78,
(11) a bacterium having a DNA comprising a base sequence at least 90% identical to SEQ ID NO:
79,
(12) a bacterium having a DNA comprising a base sequence at least 90% identical to SEQ ID NO:
80,
(13) a bacterium having a DNA comprising a base sequence at least 90% identical to SEQ ID NO:
81,
(14) a bacterium having a DNA comprising a base sequence at least 90% identical to SEQ ID NO:
82,
(15) a bacterium having a DNA comprising a base sequence at least 90% identical to SEQ ID NO:
83,
(16) a bacterium having a DNA comprising a base sequence at least 90% identical to SEQ ID NO:
84,
(17) a bacterium having a DNA comprising a base sequence at least 90% identical to SEQ ID NO:
85,
(18) a bacterium having a DNA comprising a base sequence at least 90% identical to SEQ ID NO:
86,
(19) a bacterium having a DNA comprising a base sequence at least 90% identical to SEQ ID NO:
87,
(20) a bacterium having a DNA comprising a base sequence at least 90% identical to SEQ ID NO:
88,
(21) a bacterium having a DNA comprising a base sequence at least 90% identical to SEQ ID NO:
89,
(22) a bacterium having a DNA comprising a base sequence at least 90% identical to SEQ ID NO:
90,
(23) a bacterium having a DNA comprising a base sequence at least 90% identical to SEQ ID NO:
91,
(24) a bacterium having a DNA comprising a base sequence at least 90% identical to SEQ ID NO:
92,
(25) a bacterium having a DNA comprising a base sequence at least 90% identical to SEQ ID NO:
93,
(26) a bacterium having a DNA comprising a base sequence at least 90% identical to SEQ ID NO:
94,
(27) a bacterium having a DNA comprising a base sequence at least 90% identical to SEQ ID NO:
95,
(28) a bacterium having a DNA comprising a base sequence at least 90% identical to SEQ ID NO:
96,
(29) a bacterium having a DNA comprising a base sequence at least 90% identical to SEQ ID NO:
97,
(30) a bacterium having a DNA comprising a base sequence at least 90% identical to SEQ ID NO:
98,
(31) a bacterium having a DNA comprising a base sequence at least 90% identical to SEQ ID NO:
99,
(32) a bacterium having a DNA comprising a base sequence at least 90% identical to SEQ ID NO:
100,
(33) a bacterium having a DNA comprising a base sequence at least 90% identical to SEQ ID NO:
101,
(34) a bacterium having a DNA comprising a base sequence at least 90% identical to SEQ ID NO:
102,
(35) a bacterium having a DNA comprising a base sequence at least 90% identical to SEQ ID NO:
103,
(36) a bacterium having a DNA comprising a base sequence at least 90% identical to SEQ ID NO:
104, and
(37) a bacterium having a DNA comprising a base sequence at least 90% identical to SEQ ID NO:
105,
as an active ingredient, and wherein said antibacterial composition further comprises a medium and/or a buffer.

72 more elements

Anti-bacterial composition against TH1 cell-inducing bacteria

Life of this patent

Anti-bacterial composition against TH1 cell-inducing bacteria

Life of this patent

Abstract

Claims4