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AssigneeChiesi Farmaceutici S.p.A.
InventorsClive Arthur Arculus-Meanwell, Simona Skerjanec, Jayne Prats
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Methods of treating, reducing the incidence of, and/or preventing an ischemic event in a patient undergoing percutaneous coronary intervention (PCI), comprising administering to the patient a pharmaceutical composition comprising cangrelor. The method may further comprise administering an additional therapeutic agent to the patient, the additional therapeutic agent comprising bivalirudin or a P2Y12 inhibitor. Pharmaceutical compositions useful for treating, reducing the incidence of, and/or preventing an ischemic event in a patient undergoing PCI. The pharmaceutical compositions comprise cangrelor, and optionally bivalirudin. Methods of preparing a pharmaceutical composition for treating, reducing the incidence of, and/or preventing an ischemic event in a patient undergoing PCI, comprising admixing cangrelor with one or more pharmaceutically acceptable excipients. An ischemic event may include stent thrombosis, myocardial infarction, ischemia-driven revascularization, and mortality.
A method of treating an ischemic event in a patient who is being prepared for or is undergoing percutaneous coronary intervention (PCI), wherein the ischemic event is selected from the group consisting of stent thrombosis, myocardial infarction and ischemia-driven revascularization, consisting of administering to the patient a pharmaceutical composition consisting essentially of cangrelor and a pharmaceutically acceptable excipient consisting of one or more of mannitol, sorbitol, and sodium hydroxide, wherein the pharmaceutical composition is lyophilized, the lyophilized pharmaceutical composition is dissolved in an intravenous fluid and is administered to the patient intravenously.
A method of treating an ischemic event in a patient who is being prepared for or is undergoing percutaneous coronary intervention (PCI), wherein the ischemic event is selected from the group consisting of stent thrombosis, myocardial infarction, and ischemia-driven revascularization, consisting of administering to the patient a pharmaceutical composition consisting essentially of cangrelor and a pharmaceutically acceptable excipient consisting of one or more of mannitol, sorbitol, and sodium hydroxide wherein the pharmaceutical composition is lyophilized, the lyophilized pharmaceutical composition is dissolved in an intravenous fluid and is administered to the patient intravenously, and administering a P2Y12 inhibitor selected from the group consisting of clopidogrel, prasugrel, and ticagrelor.
Dependencies are inferred from the claim text.