Bodily fluid collection devices and related methods

A device for withdrawing bodily fluid from a subject, the device comprising:

• a housing including a base and a release member extending from the base, wherein the base has an opening extending therethrough;
• a skin-piercing assembly positioned at least partially within the housing, wherein the skin-piercing assembly includes—
• a trigger portion and a blade holder portion;
• a drive member pivotably coupled to the blade holder portion;
• a blade carried by the drive member;
• and
• a biasing member operably coupled to the drive member;
• a flexible sealing member positioned within the housing and defining a sealed volume within the housing over the opening in the base;
• a one-way valve coupled to the housing and configured to (a) inhibit air from entering the sealed volume from outside the device and (ii) permit air to exit the sealed volume to outside the device;
• and
• an actuator operably coupled to the skin-piercing assembly and movable from a first position to a second position relative to the housing, wherein—
• in the first position, the drive member is configured to engage the trigger portion to maintain the biasing member in a biased configuration, and
• movement of the actuator from the first position to the second position is configured to engage the trigger portion with the release member to disengage the trigger portion from the drive member to permit the biasing member to drive the blade at least partially through the opening in the base.

A device for withdrawing bodily fluid from a subject, the device comprising:

• a housing including a base having an opening extending therethrough, wherein the base is configured to be positioned adjacent skin of the subject;
• and
• a skin-piercing assembly positioned at least partially within the housing, wherein the skin-piercing assembly includes—
• a casing having a lower surface;
• a blade pivotably coupled to the casing;
• and
• a biasing member operably coupled to the blade and configured to drive the blade relative to the lower surface;
• and
• an actuator operably coupled to the skin-piercing assembly and movable relative to the housing, wherein—
• the actuator is movable to a first position to drive the lower surface of the casing at least partially through the opening in the base and into contact with the skin;
• and
• the actuator is movable to a second position to release the biasing member to permit the biasing member to drive the blade along a path through the skin and relative to the lower surface of the casing.