Apparatus and method for analyzing in vivo component and impedance measuring apparatus

An apparatus for analyzing an in vivo component, the apparatus comprising:

• an impedance sensor comprising a first electrode configured to contact a first side of a fluid channel of a fluid to be analyzed, and a second electrode configured to contact a second side of the fluid channel, wherein the first side and the second side of the fluid channel oppose each other;
• an impedance measurement device configured to:
• apply a current to the first electrode and the second electrode;
• measure a voltage between the first electrode and the second electrode based on applying the current;
• and
• measure an impedance of the fluid based on the measured voltage while the fluid is flowing through the fluid channel disposed between the first electrode and the second electrode, during a state in which the impedance sensor is in contact with an object;
• a memory configured to store a parameter at a reference time;
• and
• a processor configured to:
• model an equivalent circuit equivalent to the impedance measured at an estimation time after the reference time;
• and
• analyze the in vivo component based on the modeled equivalent circuit,
• wherein the processor is further configured to:
• extract one or more parameters, related to properties of the fluid to be analyzed, based on the modeled equivalent circuit;
• obtain a parameter variation by normalizing the extracted one or more parameters using the parameter at the reference time stored in the memory;
• obtain an in vivo component value, including at least one of blood glucose, cholesterol, triglyceride, protein, and uric acid, by applying an in vivo component estimation model to the parameter variation, and
• wherein the one or more parameters comprise at least one of plasma resistance, cytoplasm resistance, plasma capacitance, and constant phase element (CPE) of a cell membrane.