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US 11,633,099 B2Granted
Internet-based cognitive diagnostics using visual paired comparison task
AssigneeEmory University
InventorsYevgeny E. Agichtein, Elizabeth A. Buffalo, Dmitry Lagun, Cecelia Manzanares, Stuart Zola
Life of this patent
Estimating the term…
Abstract
Disclosed are methods for diagnosing declarative memory loss using mouse tracking to follow the visual gaze of a subject taking a visual paired comparison test. Also disclosed are methods for diagnosing dementia such as mild cognitive impairment and Alzheimer's disease.
Claims22
A method for distinguishing the diagnosis of Parkinson's disease from the diagnosis of cognitive impairment in a subject comprising:
- a. conducting a visual paired-comparison (VPC) test on a computer based system, the VPC test including one or more trials, each trial simultaneously displaying areas of interest of a novel image to a subject and displaying areas of interest in a familiar image to both eyes of the subject;
- b. receiving in an application server eye movement characteristics for the subject for each trial from the computer based system during the VPC test by the subject, wherein the eye movement characteristics are associated with the areas of interest of the novel image and the areas of interest of the familiar image;
- and
- c. detecting in the application server whether the eye movement characteristics for the subject match a classifier associated with cognitive impairment that is different from a classifier associated with Parkinson's disease.
1 more element
A system for distinguishing the diagnosis of Parkinson's disease from the diagnosis of cognitive impairment in a subject, comprising
- a. a computer based system for conducting a visual paired-comparison (VPC) test, the VPC test including one or more trials, wherein each trial simultaneously displays areas of interest of a novel image to a subject and displays areas of interest in a familiar image to both eyes of the subject;
- and
- b. an application server coupled to the computer based system for receiving eye movement characteristics for the subject for each trial from the computer based system during the VPC test by the subject, wherein the eye movement characteristics are associated with the areas of interest of the novel image and the areas of interest of the familiar image, and the eye movement characteristics for the subject match a classifier associated with cognitive impairment that is different from a classifier associated with Parkinson's disease.
Dependencies are inferred from the claim text.