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US 11,632,951 B2Granted
Apparatus for tissue transport and preservation
AssigneeParagonix Technologies, Inc.
InventorsAdam Collette, Melanie Jessel, Lisa Maria Anderson
Life of this patent
Estimating the term…
Abstract
Systems and methods of the invention generally relate to prolonging viability of bodily tissue, especially an organ such as a lung, by adjusting pressure as needed to maintain a constant pressure within the organ even during external pressure fluctuations due, for example, to transportation of the organ in an airplane. Gas passing into and out of the organ may be conditioned to prolong tissue viability.
Claims23
A system for storage of an organ, the system comprising:
- a pressure regulator;
- a pressure relief valve;
- and
- an organ adapter in fluid communication with the pressure regulator and the pressure relief valve and operable to form a closed air system within a lumen of an organ, the closed air system excluding an exterior of the organ,
- wherein the pressure relief valve is operable to release gas from within the closed air system in response to pressure within the closed air system above a high-pressure threshold, and
- wherein the pressure regulator is operable to add gas from a pressurized gas source to the closed air system in response to pressure within the closed air system below a low-pressure threshold;
- and
- coupling the lumen of an organ to the organ adapter to form the closed air system and operating the pressure relief valve and the pressure regulator to maintain a desired pressure differential between the closed air system and the exterior of the organ.
5 more elements
A method for storage of an organ, the method comprising:
- providing an organ container comprising:
- a pressure regulator;
- a pressure relief valve;
- and
- an organ adapter in fluid communication with the pressure regulator and the pressure relief valve and operable to form a closed air system within a lumen of an organ, the closed air system excluding an exterior of the organ,
- wherein the pressure relief valve is operable to release gas from within the closed air system in response to pressure within the closed air system above a high-pressure threshold, and
- wherein the pressure regulator is operable to add gas from a pressurized gas source to the closed air system in response to pressure within the closed air system below a low-pressure threshold, and
- coupling the lumen of an organ to the organ adapter to form the closed air system and operating the pressure relief valve and the pressure regulator to maintain a desired pressure differential between the closed air system and the exterior of the organ.
5 more elements
Dependencies are inferred from the claim text.