Techniques for determining coagulation results

An automated method for determining a coagulation result of a biological sample, the method comprising:

• obtaining a time series representing measurement data of a biological sample, wherein the time series spans a period in which a clotting reaction is supposed to take place in the biological sample;
• obtaining a global model function configured to model measurement data of a biological sample in which a clotting reaction takes place, wherein the global model function is configured to model the measurement data as a sigmoidal shape with at least one inflection point and wherein the absolute value of the maximum curvature of the sigmoidal shape is larger on one side of the at least one inflection point than on the other side;
• fitting the model function to the time series representing measurement data to obtain a fitted global model function;
• and
• determining a coagulation result of the biological sample based on the fitted global model function,
• wherein determining a coagulation result comprises
• determining a baseline of the sigmoidal shape based on the fitted global model function,
• determining a virtual or actual asymptotic line based on the fitted global model function, wherein a virtual asymptotic line is an asymptotic line that the fitted model function would approach in the absence of interfering processes and wherein at least one of the baseline and the virtual or actual asymptotic line is non-flat,
• defining a threshold line running between the baseline and the asymptotic line, wherein a distance between the baseline and the threshold line is a fixed fraction of a distance between the baseline and the virtual or actual asymptotic line at each point in time, and
• determining the coagulation result based on a feature of the fitted global model function at a point where the fitted global model function crosses the threshold line.