Electrochemical approach for COVID-19 detection

A method for diagnosing COVID-19 infection of a person, comprising:

• generating a calibration data set, comprising:
• generating a first range of current peaks, comprising:
• recording a first set of CV patterns from a plurality of persons infected with COVID-19 virus;
• and
• measuring a first set of current peaks of the first set of CV patterns;
• and
• generating a second range of current peaks, comprising:
• recording a second set of CV patterns from a plurality of persons not infected with COVID-19 virus;
• and
• measuring a second set of current peaks of the second set of CV patterns;
• acquiring a sputum sample of the person;
• measuring a level of reactive oxygen species (ROS) in the sputum sample, comprising:
• recording a cyclic voltammetry (CV) pattern from the sputum sample;
• wherein recording the CV pattern from the sputum sample comprises:
• attaching a sensing head of an electrochemical probe to a handle of the electrochemical probe, the sensing head comprising three needle-shaped electrodes located at one end of the sensing head;
• connecting the handle of the electrochemical probe to an electrochemical stimulator-analyzer device;
• inserting the three needle-shaped electrodes into the sputum sample;
• applying a sweeping range of electrical potential from −0.8 V to +0.8 V with a scan rate of 100 mVs-1 to the electrochemical probe utilizing the electrochemical stimulator-analyzer device;
• and
• recording the CV pattern comprising a set of electrical currents versus the applied sweeping range of electrical potential;
• and
• measuring a current peak of the recorded CV pattern;
• and
• detecting a COVID-19 infection status of the person based on the measured level of ROS, comprising:
• detecting that the person is infected with COVID 19 if the measured current peak is in the first range of current peaks;
• and
• detecting that the person is not infected with COVID 19 if the measured current peak is in the second range of current peaks.