Quasi-soft catcher, quasi-soft capture device, and method using the same

A quasi-soft catcher for being applied to capture at least one target biological particle from a specimen, comprising:

• a base having a board surface;
• and
• a plurality of protruding structures extending from the board surface and regularly arranged, wherein each of the protruding structures includes an outer portion configured to touch at least one target biological particle and an inner portion that is connected between the board surface and the outer portion, wherein in each of the protruding structures, a structural strength of the inner portion is less than that of the outer portion, and wherein the board surface has an interspace region arranged outside of the protruding portions, and the interspace region occupies 20-80% of the board surface;
• wherein part of the protruding structures on the board surface are distributed as a plurality of first structural groups, and each of the first structural groups defines a capture region having an N-sided polygon with a shape corresponding to the at least one target biological particle, and N is an integer larger than or equal to three;
• wherein another part of the protruding structures on the board surface are distributed as a second structural group, and the second structural group defines a buffering region arranged adjacent to at least one of the capture regions, and wherein an area of the buffering region is smaller than that of each of the capture regions.