Detection of bacteria using bacteriophage
AssigneesUniversity of Pittsburgh—Of the Commonwealth System of Higher Education, Duquesne University of the Holy Spirit
InventorsJohn Alston Kellum, John D. Hempel, Robert Hugh Edgar, John Andrew Viator
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Abstract
A method of detecting a species, strain or type of bacteria includes mixing a labeled bacteriophage including a label that is detectible via a detection system with a bacterial culture including the species, strain or type of bacteria to which the labeled bacteriophage selectively binds and using the detection system to detect the labeled bacteriophage bound to the species, strain or type of bacteria.
Claims10
A method of determining if a sample taken from a patient includes a species, strain or type of bacteria, comprising:
- mixing a labeled bacteriophage including a label that is detectible via a detection system with the sample, the labeled bacteriophage being active to selectively bind with the species, strain or type of bacteria, applying light energy to the sample to generate photoacoustic waves, and measuring the generated photoacoustic waves to determine the presence of the labeled bacteriophage bound to the species, strain or type of bacteria.
Dependencies are inferred from the claim text.