Microfluidic rotor device
AssigneeZoetis Services LLC
InventorsRobert Justice Shartle, Gregory Trigub
Life of this patent
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Abstract
Described herein are various embodiments directed to rotor devices, systems, and kits. Embodiments of rotors disclosed herein may be used to characterize one or more analytes of a fluid. An apparatus may include a first layer being substantially transparent. A second layer may be coupled to the first layer. The second layer may be substantially absorbent to infrared radiation. The second layer and the first layer may collectively define a set of wells. The first layer may define a base for each well of the set of wells. The second layer may define an opening for each well of the set of wells. At least one of the first layer and the second layer may define a sidewall for each well of the set of wells.
Claims17
An apparatus, comprising:
- a microfluidic rotor device defining a central hole and having a first layer being substantially transparent;
- and
- a second layer coupled to the first layer, the second layer being substantially absorbent to infrared radiation,
- the second layer and the first layer collectively defining a set of wells arranged at an equal distance about the central hole, the first layer defining a base for each well of the set of wells, the second layer defining an opening for each well of the set of wells, at least one of the first layer and the second layer defines a sidewall for each well of the set of wells, and the second layer defining a circular-shaped channel formed concentrically around the central hole,
- the second layer defines a set of inlets in fluid communication with the circular-shaped channel, wherein each inlet of the set of inlets corresponding to a different well of the set of wells,
- the set of inlets includes a first subset of inlets and a second subset of inlets, wherein a width of each inlet of the second subset of inlets is larger than a width of each inlet of the first subset of inlets,
- bidirectional fluid occurs using the second subset of inlets but not the first subset of inlets during spinning of the microfluidic rotor device at less than about 4,000 revolutions per minute (RPMs), wherein the bidirectional fluid flow includes liquid phase flow in a first direction and a gas phase flow in a second direction;
- wherein each inlet of the set of inlets establishes a fluid communication path between the opening and its corresponding well;
- and
- wherein a width of each inlet of the second subset of inlets is between about 0.25 mm and about 3.0 mm;
- a length of each inlet of the second subset of inlets is between about 0.5 mm and about 6.0 mm;
- a depth of each inlet of the second subset of inlets is between about 0.1 mm and about 0.25 mm.
Dependencies are inferred from the claim text.