System for achieving high-specificity killing of targeted cells and method thereof using magneto-electric nano-particles

A system for achieving high-specificity killing of targeted cells comprising:

• Magneto-Electric Nano-Particles (MENPs), wherein the MENPs are not loaded with a drug intended to kill targeted cells,
• an apparatus for injecting the MENPs into a patient's body, and
• an apparatus for applying a magnetic field to the MENPs, to generate an electric field on the MENPs through their magneto-electric coupling property due to correlated magnetostrictive and piezoelectric effects of the MENPs;
• wherein said apparatus for applying a magnetic field to the MENPs is an apparatus for applying a first magnetic field and a second magnetic field comprising a selector (or selecting module) to select the first magnetic field strength H with A<H<B where A and B are thresholds so that the MENPs achieve nano-electroporation to penetrate targeted cells but no or little nano-electroporation of non-targeted cells and to select the second magnetic field strength to induce the MENPs to generate one or more disruptive actions to disrupt the function of the targeted cells, including an electric gradient field, an alternating electric field, an alternating electric field at one or more ferromagnetic resonance frequency(ies) of the MENPs.