System and method for microneedle delivery of microencapsulated vaccine and bioactive proteins
AssigneeThe Corporation of Mercer University
InventorMartin J. D'Souza
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AssigneeThe Corporation of Mercer University
InventorMartin J. D'Souza
Estimating the term…
A method for producing at least one microneedle containing a vaccine for transdermal delivery of the vaccine to a patient includes preparing microparticles or nanoparticles of encapsulated vaccine by preparing a solution comprising a vaccine antigen and a biocompatible polymer matrix; and spray drying the solution to form the microparticles or nanoparticles. The method includes the further steps of preparing a film composition including at least one pre-polymer solution; preparing a suspension comprising the microparticles or nanoparticles and the film composition; loading the suspension into a 3D printer; printing, via the 3D printer, at least one microneedle made from the suspension; and, converting the pre-polymer solution into a cross-linked biopolymer by exposing the at least one microneedle to UV light. Also disclosed are microneedles containing a vaccine for transdermal delivery.
A method of producing at least one microneedle comprising a vaccine for transdermal delivery of the vaccine to a patient, comprising:
A microneedle for transdermal delivery of a bioactive material, comprising:
A microneedle for transdermal delivery of a bioactive material, comprising:
Dependencies are inferred from the claim text.