Highly purified fucans for the treatment of fibrous adhesions
AssigneeARC Medical Ine.
InventorsChristopher Michael Kevin Springate, Ian Millet, Sailesh Haresh Daswani, Hesong Sun, Aileen Shao Ting Yang, Hoi Ting Wong
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Abstract
Compositions, methods, systems, etc., are provided for modified and/or purified fucans and corresponding fucan-containing compositions that inhibit fibrous adhesions among other advantages. The purified/modified fucans and fucan compositions have a reduced level of non-fucan components or impurities such as those found in a starting fucan composition. Such reduced undesirable components or impurities include, for example, undesired components bound to the fucan and compounds in the composition that are not a part of or bound to the fucan.
Claims32
A purified and modified, medically acceptable fucan comprising a purified and modified fucan polymeric structure and counterions, wherein the purified and modified fucan polymeric structure consists essentially of fucose, galactose and sulfate, and wherein the purified and modified fucan comprises no more than about 17% counterions, and wherein a total content of fucose, galactose, sulfate and counterions of the purified and modified fucan is greater than 97% w/w.
Dependencies are inferred from the claim text.