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US 11,628,143 B1Granted
Tablet for oral suspension
AssigneeNovitium Pharma LLC
InventorsMuthusamy Shanmugam, Shivanand Premanand Puthli
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Abstract
Disclosed herein is a tablet for oral suspension comprising carglumic acid and its use.
Claims19
A tablet for oral suspension, comprising:
- carglumic acid in an amount of about 200 mg;
- a diluent comprising microcrystalline cellulose, mannitol, or a combination thereof in an amount of from 228 mg to 280 mg;
- a suspending agent comprising a povidone having a weight average molecular weight of from 44 kDa to 54 kDa in an amount of from 4.4 mg to about 5.4 mg;
- a disintegrant comprising sodium croscarmellose in an amount of from 17 mg to 21 mg;
- a wetting agent comprising sodium stearyl fumarate, magnesium stearate, sodium lauryl sulfate, or a combination thereof in an amount of from 6.35 mg to 7.65 mg;
- and
- a glidant comprising colloidal silicon dioxide in an amount of from 2.3 mg to 2.8 mg;
- wherein the tablet does not include tromethamine or an effervescent agent.
5 more elements
A method of treating chronic hyperammonaemia, which comprises administering to a patient in need thereof a therapeutically effective amount of the oral suspension of claim.
Dependencies are inferred from the claim text.