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US 11,628,138 B2Granted
Steroidal compositions and method of making and use
AssigneeFarmakeio Outsourcing LLC
InventorsCody Boatman, Daniel DeNeui, Justin Graves
Life of this patent
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Abstract
Disclosed herein are compositions useful for treating hypogonadism in men and women. The disclosed compositions comprise an admixture of testosterone and triamcinolone which combination alleviates pellet injection site pain and/or discomfort, as well as pellet extrusion.
Claims22
An implantable pharmaceutical composition, consisting of:
- a) from about 10 mg to about 250 mg by weight of testosterone;
- b) from about 1 μg to about 50 μg by weight of triamcinolone;
- and
- c) from about 0.4 mg to about 12 mg of stearic acid, ethylcellulose or mixtures thereof.
1 more element
An implantable pharmaceutical composition, consisting of:
- a) about 95.3% by weight of testosterone;
- b) about 0.02% by weight of triamcinolone;
- and
- c) about 3.8% by weight of stearic acid and 0.86% by weight of ethyl cellulose.
1 more element
A method for treating a subject in need of an increased testosterone level, comprising contacting the subject with a composition consisting of:
- a) from about 10 mg to about 250 mg by weight of testosterone;
- b) from about 1 μg to about 50 μg by weight of triamcinolone;
- c) from about 0.5 mg to about 12.5 mg by weight of stearic acid;
- and
- d) from about 0.113 mg to about 1.8 mg by weight of ethylcellulose.
2 more elements
Dependencies are inferred from the claim text.