US 11,628,137 B2Granted

Parenteral formulation comprising siponimod

AssigneeNovartis AG

InventorsRajesh Kumar, Mandala Rayabandla Sunil Kumar, Henricus Lambertus Gerardus Maria Tiemessen

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Abstract

The present invention relates to a pharmaceutical formulation of siponimod which can be administered parenterally. In particular, the present invention relates to a parenteral solution comprising siponimod and a method for preparing said solution.

Claims17

Dependent claims

A liquid parenteral formulation, comprising:

(A) siponimod, (B) cyclodextrin, (C) buffer agent and (D) solvent.

Dependencies are inferred from the claim text.

Facts

Application: 16/650,803Filed 26 Sep 2018
Priority: IN 20171103437127 Sep 2017
Published: US 2020/0230049 A123 Jul 2020
Granted: 18 Apr 2023
Term ends: Not estimatedThe source records don’t support an estimate.

Classification9 codes

A61K 9/0019
Galenical forms characterised by the site of application: injectable compositions; Intramuscular, intravenous, arterial, subcutaneous…
A61K 9/08
Medicinal preparations characterised by special physical form: solutions
A61K 31/397
Having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins: having four-membered rings, e.g. azetidine
A61K 31/724
Glucans: cyclodextrins

Family

US 2020/0230049 A1Pre-grant publication · published 23 Jul 2020
US 11,628,137 B2This patent

From the US filing history. Foreign family members aren’t listed.

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