Uses of the peptide of sequence His-D-Trp-Ala-Trp-d-Phe-Lys-NH2 for reducing or delaying the appearance of cell senescence and signs of skin aging
AssigneeISP Investments Inc.
InventorsNouha Domloge, Catherine Gondran, Ludivine Mur
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Abstract
The present invention relates to the cosmetic use of a composition including, as the active agent, 0.1 to 1 μM of a synthetic peptide of sequence His-D-Trp-Ala-Trp-D-Phe-Lys-NH2 or one of the salts thereof in a physiologically suitable medium, in order to reduce or delay the appearance of cell senescence and signs of skin aging. The present invention also relates to a method for cosmetic treatment which relates to these novel uses, including comprising the steps of applying the composition, topically, at least once per day, for a period of at least two days.
Claims9
A method for increasing the activity of prolidase and the synthesis of collagen in skin, the method comprising topically applying a composition comprising, as the only active agent, between 0.1 and 1 μM of a synthetic peptide with sequence His-D-Trp-Ala-Trp-D-Phe-Lys-NH2 (SEQ ID NO:
- 1) or one of its salts in a physiologically acceptable medium, wherein the composition is applied topically, at least once per day, for a period of at least 2 days.
A cosmetic treatment method for reducing or delaying the appearance of cellular senescence and the signs of skin aging, the method comprising the topical application, at least once per day over a period of at least 2 days, of a composition comprising, as the only active agent, between 0.1 and 1 μM of a synthetic peptide with the sequence His-D-Trp-Ala-Trp-D-Phe-Lys-NH2 (SEQ ID NO:
- 1) in a physiologically acceptable medium, where the composition increases the activity of prolidase and the synthesis of collagen.
Dependencies are inferred from the claim text.