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US 11,627,738 B2Granted
Stimuli-responsive polymeric nanoparticles, methods of making stimuli-responsive polymeric nanoparticles, and methods of using stimuli-responsive polymeric nanoparticles
AssigneeUniversity of Florida Research Foundation, Inc.
InventorsBrent S. Sumerlin, Shaun Paul Jensen, Megan R. Hill, Mingsheng Chen, Gloria A Moore, Zhenli L He, Sangwoo Park
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Abstract
Embodiments of the present disclosure provide for compositions including polymer particles, methods of making compositions, methods of using the composition, stimuli-responsive methods of delivering agents, and the like.
Claims3
A method, comprising:
- exposing a plant to a composition comprising a particle comprising a star polymer and an agent, wherein the star polymer is selected from poly(aspartic acid)-polysuccinimide (PASP-PSI) and polysuccinimide-hexyl amine (PSI-HA), wherein the star polymer has a core and 3 to 50 arms extending from the core, wherein the core is a responsive unit and the arms are a hydrophilic unit, wherein the particle is not agglomerated, and wherein the polymer particle has a diameter of about 10 to 50 nm, wherein the particle is amphiphilic and the agent is encapsulated by the star polymer;
- and
- releasing the agent when the particle is exposed to:
- a change in the pH environment around the particle from a pH of about 6-6.5 to a pH of about 7-8.5 and changes the particle from hydrophobic to hydrophilic;
- a change in the sugar level around the particle from about 1 mM to about 10 mM or more and changes the particle from hydrophobic to hydrophilic;
- or a combination thereof in a plant.
3 more elements
Dependencies are inferred from the claim text.