Compounds
AssigneeInflazome Limited
InventorsDavid Miller, Stephen Thom, Stephen St-Gallay, Jonathan Shannon, Paul Leeson
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AssigneeInflazome Limited
InventorsDavid Miller, Stephen Thom, Stephen St-Gallay, Jonathan Shannon, Paul Leeson
Estimating the term…
The present invention relates to compounds of formula (I): wherein Q is selected from O or S; R1 is a saturated or unsaturated hydrocarbyl group, wherein the hydrocarbyl group may be straight-chained or branched, or be or include cyclic groups, wherein the hydrocarbyl group may optionally be substituted, and wherein the hydrocarbyl group may optionally include one or more heteroatoms N, O or S in its carbon skeleton; and R2 is a cyclic group substituted at the a-position, wherein R2 may optionally be further substituted. The present invention further relates to salts, solvates and prodrugs of such compounds, to pharmaceutical compositions comprising such compounds, and to the use of such compounds in the treatment and prevention of medical disorders and diseases, most especially by the inhibition of NLRP3.
A compound of formula (I):
A compound selected from the group consisting of:
Dependencies are inferred from the claim text.