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US 11,617,968 B2Granted
Sample clean up device and method
AssigneeBiotage AB
InventorsGeoff Davies, Adam Senior, Lee Williams, Rhys Jones
Life of this patent
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AssigneeBiotage AB
InventorsGeoff Davies, Adam Senior, Lee Williams, Rhys Jones
Estimating the term…
The present invention relates to a flow-through device comprising at least one separation column wherein a first packing component, which comprises particles of alumina and/or silica, and a second packing component, which comprises a powder of one or more hygroscopic salts are provided. The two packing components may be blended or layered in the device, which may comprise a single tube or a plurality of tubes arranged in a plate format, such as the wells of a multiwall plate or tubes in a rack. In addition, the invention relates to a method for removing one or more matrix components, such as pigments, from a biological sample, by passing said sample across a first packing component, which comprises particles of alumina and/or silica, and a second packing component, which comprises a powder of one or more hygroscopic salts.
A flow-through device comprising at least one separation column, wherein a first packing component, which comprises particles of alumina and/or silica, and a second packing component, which comprises a powder of one or more hygroscopic salts, are provided such that at least a portion of the second packing component is downstream of a least a portion of the first packing component,
A method for removing one or more matrix components from a biological sample, wherein said matrix components are one or more selected from the group consisting of urea;
A method of using of a mixture of a first packing component, which comprises
Dependencies are inferred from the claim text.