Systems and methods for managing glycemic variability

A system comprising:

• at least one processor;
• and
• at least one memory including code which when executed by the at least one processor causes the processor to perform a method, the method comprising:
• receiving input indicative of one or more insulin infusion sites on a patient;
• calculating one or more glucose control metrics for each of the one or more insulin infusion sites, the calculating based on continuous glucose sensor data indicative of the glucose concentration of the patient, the continuous glucose sensor data generated by one or more continuous glucose sensors, wherein the glucose control metrics comprise a glycemic variability index (GVI) value representative of the patient's glucose variability during a timeframe and a clinical relevance score representative of a clinical significance of the continuous glucose sensor data;
• automatically outputting information for display on a user interface including the calculated GVI and the clinical relevance score for each of the one or more insulin infusion sites;
• and
• transmitting a signal for controlling insulin delivery to an insulin delivery device inserted into an optimal insulin infusion site of the one or more insulin infusion sites, wherein the optimal insulin infusion site is based on the glucose control metrics.