System and method for cell evaluation, and cell evaluation program
AssigneesThinkCyte K.K., The University of Tokyo
InventorsMasashi Ugawa, Yoko Kawamura, Sadao Ota
Life of this patent
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Abstract
A cell evaluation system includes physical measurement unit, a database, and evaluation unit. The evaluation unit refers to a relevance stored in the database, searches reference measurement information based on measurement information of a cell newly measured via the physical measurement unit, and evaluates the cell with biological measurement information associated with the searched reference measurement information.
Claims10
A cell evaluation system comprising:
- physical measurement means that performs a physical measurement by:
- irradiating individual cells in a cell group as a measurement object flowing in a flow passage with either a structured excitation light or a structured illuminating light;
- individually interacting the cells in the cell group with either the excitation light or the illuminating light in time series;
- and
- mapping optical space information of the cells in time series waveforms of signal strength;
- a database that stores a relevance configured in at least three levels, each of the at least three levels of relevance indicating a degree of relevance between the time series waveforms of signal strength as measurement information measured by the physical measurement means and cell identification information;
- and
- evaluation means that refers to the relevance stored in the database, and identifies the cell identification information of a newly measured cell by performing an operation of selecting at least one piece of the cell identification information based on the time series waveform of signal strength as the measurement information of the newly measured cell measured via the physical measurement means.
A cell evaluation method comprising:
- performing a physical measurement by irradiating individual cells in a cell group as a measurement object flowing in a flow passage with either a structured excitation light or a structured illuminating light, individually interacting the cells in the cell group with either the excitation light or the illuminating light in time series, and mapping optical space information of the cells in time series waveforms of signal strength;
- storing, in a database, a relevance configured in at least three levels, each of the at least three levels of relevance indicating a degree of relevance between the time series waveforms of signal strength as measurement information measured by performing the physical measurement and cell identification information;
- and
- performing an evaluation by referring to the relevance stored in the database, and identifying the cell identification information of a newly measured cell by performing an operation of selecting at least one piece of the cell identification information based on the time series waveform of signal strength as the measurement information of the newly measured cell measured by performing the physical measurement.
A non-transitory computer-readable recording medium storing a program that is executable by a computer to control the computer to execute processes comprising:
- performing a physical measurement by irradiating individual cells in a cell group as a measurement object flowing in a flow passage with either a structured excitation light or a structured illuminating light, individually interacting the cells in the cell group with either the excitation light or the illuminating light in time series, and mapping optical space information of the cells in time series waveforms of signal strength
- storing, in a database, a relevance configured in at least three levels, each of the at least three levels of relevance indicating a degree of relevance between the time series waveforms of signal strength as measurement information measured by performing the physical measurement and cell identification information;
- and
- performing an evaluation by referring to the relevance stored in the database, and identifying the cell identification information of a newly measured cell by performing an operation of selecting at least one piece of the cell identification information based on the time series waveform of signal strength as the measurement information of the newly measured cell measured by performing the physical measurement.
Dependencies are inferred from the claim text.