Back to results
US 11,597,900 B2Granted
Variable diameter bioreactors
AssigneeLonza Ltd.
InventorsMichael Mietzner, Rajesh Beri, Edward Gunderson
Life of this patent
Estimating the term…
Abstract
A variable diameter bioreactor vessel is provided that includes a first vessel section having a first diameter configured to hold a liquid media and biologic material, and a second vessel section having a second diameter that is greater than the first diameter such that the liquid media can be increased from a first volume to a second volume within the vessel.
Claims19
A variable diameter bioreactor vessel configured for mammalian cell production, cellular biologic material, or live cells, the variable diameter bioreactor vessel comprising:
- a first vessel section having a first diameter configured to hold a liquid medium and biologic material;
- a second vessel section, wherein the second vessel section is situated such that the liquid medium and biologic material can be increased from a first volume to a second volume within the vessel, wherein the vessel has a base that is narrow than a top of the vessel;
- and
- at least one agitator, wherein the variable diameter bioreactor vessel has a bioreactor height and a minimum aspect ratio of greater than 0.3:1 at every bioreactor height.
1 more element
Dependencies are inferred from the claim text.