Antibody variable domains and antibody constructs
AssigneesCity of Hope, Board of Regents, The University of Texas System
InventorsHong Qin, Larry W. Kwak, Guowei Wei
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Abstract
Provided herein are, inter alia, compositions and methods for the treatment of cancer. The compositions include, for example, an antibody variable domain or antibody construct, inter alia, useful for targeting and killing cancer cells. Due to their ability to differentially bind cancer cells versus non-cancer cells, the compositions provided herein may be used, for example, for therapeutic and diagnostic purposes.
Claims16
An antibody light chain variable domain comprising SEQ ID NO:5.
An antibody construct comprising a first antibody peptide, said first antibody peptide comprising:
- (i) a first antibody light chain variable domain comprising SEQ ID NO:
- 5;
- and
- (ii) a first antibody domain bound to said first antibody light chain variable domain.
Dependencies are inferred from the claim text.