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US 11,597,743 B2Granted
Glycosyltransferase inhibitors for treatment of solid tumors
AssigneesCalifornia Institute of Technology, University of Tennessee Research Foundation
InventorsWilliam M. Clemons, Michio Kurosu
Life of this patent
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Abstract
The present invention relates to methods of treating bacterial infections and cancer in a subject in need thereof, comprising administering to the subject a therapeutically effective amount of a compound of Formula I. Also provided are methods of inhibiting dolichyl-phosphate N-acetylglucosaminephosphotransferase (DPAGT1) in an individual in need thereof, comprising administering to the individual a therapeutically effective amount of a compound of Formula I:
Claims2
A compound that is
- or a pharmaceutically acceptable salt thereof.
Dependencies are inferred from the claim text.