Use of microbial communities for human and animal health
AssigneesMicrobial Resource Management Health NV (MRM Health), Universiteit Gent
InventorsSam Possemiers, Massimo Marzorati, Tom Van De Wiele, Ilse Scheirlinck, Pieter Van Den Abeele, Selin Bolca, Davide Gottardi
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Abstract
The disclosure relates to a mixture of bacteria belonging to at least six or seven different and specific bacterial species preferably for use in preventing or treating gastro-intestinal disorders. Preferably, the mixture of bacteria is grown together in a fermenter prior to administering the mixture to a subject in order to prevent or treat the disorder.
Claims24
A method for reduction of symptoms associated with a gastro-intestinal disorder, comprising:
- orally administering a pharmaceutical composition to a subject having the gastro-intestinal disorder, wherein the pharmaceutical composition comprises:
- a mixture of bacterial species that are purified and present in an effective amount for increasing butyrate when measured by gas chromatography after 48 hours of in vitro growth in a culture compared to measurement of butyrate generated by an equivalent amount of any one strain of the bacterial species alone, and wherein the mixture of bacterial species comprises:
- Lactobacillus plantarum;
- Anaerostipes caccae;
- and
- Faecalibacterium prausnitzii.
A method for reduction of inflammatory intestinal bacteria in a subject, comprising:
- orally administering to the subject a pharmaceutical composition, wherein the pharmaceutical composition comprises:
- a mixture of bacterial species that are purified and present in an effective amount for increasing butyrate when measured by gas chromatography after 48 hours of in vitro growth in a culture compared to measurement of butyrate generated by an equivalent amount of any one strain of the bacterial species alone, wherein the mixture of bacterial species comprises:
- Lactobacillus plantarum;
- Anaerostipes caccae;
- and
- Faecalibacterium prausnitzii.
Dependencies are inferred from the claim text.