Methods for treating virus infection or proliferation
AssigneesHoward University, Georgetown University
InventorsHemayet Ullah, Sivanesan Dakshanamurthy
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Abstract
A method for treating against, or at least inhibiting or suppressing, the proliferation of an internal ribosome entry site-utilizing virus (IRES-utilizing virus) involves administering a compound, a tautomer, or a pharmaceutically acceptable salt thereof, in an amount effective for inhibiting replication of the IRES-utilizing virus in cells, wherein the compound is represented by the formula: wherein each R1 is independent of the other and represents a halogen atom selected from the group consisting of bromo, chloro, fluoro and iodo.
Claims11
A method for inhibiting the replication of a virus that utilizes an internal ribosome entry site in its replication, comprising administering a compound, a tautomer, or a pharmaceutically acceptable salt thereof, in an amount effective for inhibiting replication of the virus in cells, wherein the compound is represented by the formula:
- wherein each R1 is independent of the other and represents a halogen atom selected from the group consisting of bromo, chloro, fluoro and iodo.
A RACK1 inhibitor comprising a compound, a tautomer, or a pharmaceutically acceptable salt thereof for inhibiting replication of an internal ribosome entry site-utilizing virus in cells, wherein the compound is represented by the following formula:
- wherein each R1 is independent of the other and represents a halogen atom selected from the group consisting of bromo, chloro, and iodo.
Dependencies are inferred from the claim text.