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AssigneeAnnovis Bio, Inc.
InventorMaria Maccecchini
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The invention relates in part to a method of maintaining heavy metal homeostasis in healthy humans, comprising chronically administering to healthy humans a pharmaceutical composition consisting of from about 1 mg to less than about 200 mg of Posiphen or a pharmaceutically acceptable salt thereof together with one or more pharmaceutically acceptable excipients, on a once a day basis. By virtue of this method, prophylactic treatment of a potential disease state such as a neurodegenerative disease, cardiovascular homeostasis, cancer, vital organ homeostasis, and the like. The invention also relates in part to a method of restoring heavy metal homeostasis in sick patients, comprising chronically administering to a sick patient a pharmaceutical composition consisting of from about 1 mg to less than about 200 mg of Posiphen or a pharmaceutically acceptable salt thereof together with one or more pharmaceutically acceptable excipients, on a once a day basis. By virtue of this method, treatment of a potential disease state such as a neurodegenerative disease, cardiovascular disease, cancer, vital organ dysfunction and heavy metal dis-homeostasis, and the like.
A method of maintaining heavy metal homeostasis avoiding the effect of toxic levels of a heavy metal in cells in a healthy human or restoring heavy metal homeostasis in a sick human patient, consisting of chronically administering to a human who is at risk of or has abnormally high levels of a heavy metal and who has not been diagnosed with a neurological disease a pharmaceutical composition from 1 to 4 times daily, the pharmaceutical composition consisting of from about 1 mg to less than about 200 mg of Posiphen, and pharmaceutically acceptable salts thereof, together with one or morepharmaceutically acceptable excipients in a therapeutically effective amount to thereby maintain heavy metal homeostasis in the human and avoid the effects of toxic levels of the heavy metal in the human, wherein the heavy metal is selected from the group consisting of iron, copper, zinc and a combination of any of the foregoing.
Dependencies are inferred from the claim text.