Polymer based formulation for release of drugs and bioactives at specific GIT sites

A polymer capsule for delivery of an active pharmaceutical ingredient (API) consisting of:

• a shell formed of a plurality of layers from a dried solution of from 0.01 to 10% w/v of at least one polymer selected from HPMC, CMC, PVA, starch or a combination thereof, and from 2-6% w/v of sodium alginate cross-linked with from 0.025 to 18% w/v of bivalent ions, trivalent ions or a combination thereof, the remainder with water,
• wherein the capsule contains the API inside the capsule, and wherein the capsule prevents release of the API in the acid environment of the stomach.