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US 11,596,595 B2Granted
Intravesical drug delivery device with retention frame and drug tablets
AssigneeTARIS Biomedical LLC
InventorsHeejin Lee, Cheryl Larrivee-Elkins
Life of this patent
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Abstract
Intravesical drug delivery devices that include a device body, a number of solid drug tablets, and a retention frame. The device body includes a drug reservoir lumen and a retention frame lumen. The drug tablets is positioned in the drug reservoir lumen, and the retention frame is positioned in the retention frame lumen.
Claims21
An intravesical drug delivery device comprising:
- a device body comprising (i) a drug reservoir tube that defines a drug reservoir lumen, and (ii) a retention frame tube that defines a retention frame lumen;
- a plurality of tablets which comprise a drug, the tablets positioned in the drug reservoir lumen;
- and
- a retention frame positioned in the retention frame lumen,
- wherein the drug tablets are uniform in size and shape and tall enough to retain their orientation once loaded in the drug reservoir lumen, but short enough to provide enough interstices so that the device can flex or move along its length.
2 more elements
An intravesical drug delivery device comprising:
- a device body comprising (i) a drug reservoir tube that defines a drug reservoir lumen, and (ii) a retention frame tube that defines a retention frame lumen;
- a plurality of tablets which comprise a drug, the tablets positioned in the drug reservoir lumen;
- and
- a retention frame positioned in the retention frame lumen,
- wherein each of the plurality of tablets has a diameter from 1.0 mm to 3.2 mm and a length from 1.7 mm to 4.8 mm.
2 more elements
An intravesical drug delivery device comprising:
- a device body comprising (i) a drug reservoir tube that defines a drug reservoir lumen, and (ii) a retention frame tube that defines a retention frame lumen;
- a plurality of tablets which comprise a drug, the tablets positioned in the drug reservoir lumen;
- and
- a retention frame positioned in the retention frame lumen,
- wherein the drug reservoir tube comprises an aperture in a sidewall of the drug reservoir tube, the aperture being configured to release the drug following at least partial solubilization of the plurality of the drug tablets, and
- wherein the aperture is located on a side of the drug reservoir tube that opposes a side on which the retention frame tube is located.
3 more elements
Dependencies are inferred from the claim text.