Decellularized biologically-engineered tubular grafts
AssigneeRegents of the University of Minnesota
InventorsRobert Tranquillo, Zeeshan Syedain, Lee Meier
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Abstract
This disclosure describes decellularized, biologically-engineered tubular grafts and methods of making and using such decellularized, biologically-engineered tubular grafts.
Claims6
A biologically engineered tubular product formed from cell-produced extracellular matrix cultured under conditions that comprise providing or allowing a fibrin gel composition, as it remodels into the cell-produced extracellular matrix, to axially shorten while circumferentially stretching or distending the fibrin gel composition, thereby producing the biologically engineered tubular product, said biologically engineered tubular product selected from the group consisting of a peripheral graft;
- a urethra graft;
- a fallopian tube graft;
- a Vas deferens graft;
- a Eustachian tube graft;
- an AV graft;
- an arterial graft;
- and any tubular structure configured for insertion in a human body.
Dependencies are inferred from the claim text.