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US 11,596,468 B2Granted
Intraosseous nerve treatment
AssigneeRelievant Medsystems, Inc.
InventorsRichard Pellegrino, Paula Papineau, John S. Crombie, Samit Patel, Thomas Ryan
Life of this patent
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Abstract
Methods and systems for modulating intraosseous nerves (e.g., nerves within bone) are provided. For example, the methods and systems described herein may be used to modulate (e.g., denervate, ablate) basivertebral nerves within vertebrae. The modulation of the basivertebral nerves may facilitate treatment of chronic back pain. The modulation may be performed by a neuromodulation device an energy delivery device).
Claims12
A method of treating back pain in a patient, the method comprising:
- inserting a cannula through an outer cortical bone region of a vertebral body and into an inner cancellous bone region of the vertebral body;
- inserting a distal end portion of a first energy delivery device having two electrodes through and out of an open distal tip of the cannula and within the inner cancellous bone region of the vertebral body,
- wherein the two electrodes comprise a pair of bipolar electrodes,
- wherein a first electrode of the pair of bipolar electrodes is configured to function as an active electrode,
- wherein a second electrode of the pair of bipolar electrodes is configured to function as a return electrode;
- positioning the first electrode on a first side of a basivertebral nerve within the cancellous bone region of the vertebral body and positioning the second electrode on a second side of the basivertebral nerve;
- applying pulsed energy using the first energy delivery device by generating a sufficiently high voltage difference between the first electrode and the second electrode for a sufficient duration to the basivertebral nerve within the vertebral body to treat back pain,
- wherein the high voltage difference is in the range from 50 to 1500 volts,
- wherein the sufficient duration is between 5 minutes and 30 minutes, and
- wherein the sufficiently high voltage difference produces a total heating zone having a diameter of at least 0.5 cm and a peak temperature of between 70 degrees Celsius and 90 degrees Celsius.
7 more elements
A method of treating pain in a patient, the method comprising:
- inserting a cannula through an outer cortical bone region of a bone and into an inner cancellous bone region of the bone;
- inserting a distal end portion of an energy delivery device having two electrodes through and out of an open distal tip of the cannula and within the inner cancellous bone region of the bone,
- positioning a first electrode of the two electrodes on a first side of an intraosseous nerve within the cancellous bone region of the bone and positioning a second electrode of the two electrodes on a second side of the intraosseous nerve;
- and
- applying pulsed energy using the energy delivery device by generating a sufficiently high voltage difference between the first electrode and the second electrode for a sufficient duration to modify the intraosseous nerve within the bone,
- wherein the high voltage difference is in the range from 50 to 1500 volts,
- wherein the sufficient duration is between 5 minutes and 30 minutes, and
- wherein the sufficiently high voltage difference produces a total heating zone having a diameter of at least 0.5 cm and a peak temperature of between 70 degrees Celsius and 90 degrees Celsius.
5 more elements
Dependencies are inferred from the claim text.