Apparatus and method for estimating analyte concentration

#This application claims is based on and claims priority under 35 U.S.C. § 119 to Korean Patent Application No. 10-2018-0118260, filed on Oct. 4, 2018, in the Korean Intellectual Property Office, the disclosure of which is incorporated by reference herein in its entirety.

#The following description relates to an apparatus and method for estimating a concentration of an in vivo analyte using a bio-signal.

#Diabetes mellitus is a chronic disease which is difficult to treat and causes various complications, and hence a blood glucose level should be checked regularly to prevent complications. When insulin is administered, blood glucose should be checked in order to prevent hypoglycemia and control the insulin dosage. Generally, measuring blood glucose requires an invasive method such as drawing blood with a finger prick. The method of measuring blood glucose in an invasive manner has high reliability of measurement, but the use of injection may cause pain during blood sampling, inconvenience, and a risk of infection. Recently, a method of non-invasive measurement of blood glucose using an optical sensor, without directly collecting blood, has been studied.

#The above and other aspects, features, and advantages of certain embodiments of the present disclosure will be more apparent from the following description taken in conjunction with the accompanying drawings, in which:

#FIGS. 1 and 2 are diagrams for describing a concept of a general net analyte signal (NAS) algorithm.

#FIG. 3 is a block diagram illustrating an apparatus for estimating a concentration of an in vivo analyte according to an embodiment.

#Throughout the drawings and the detailed description, unless otherwise described, the same drawing reference numerals may refer to the same elements, features, and structures. The relative size and depiction of these elements may be exaggerated for clarity, illustration, and convenience.

#The following detailed description is provided to assist the reader in gaining a comprehensive understanding of the methods, apparatuses, and/or systems described herein. Various changes, modifications, and equivalents of the systems, apparatuses, and/or methods described herein should be apparent to those of ordinary skill in the art. In the following description, a detailed description of known functions and configurations incorporated herein may be omitted so as to not obscure the subject matter of the present disclosure. Throughout the drawings and the detailed description, unless otherwise described, the same drawing reference numerals may refer to the same elements, features, and structures. The relative size and depiction of these elements may be exaggerated for clarity, illustration, and convenience.

#It should be noted that in some implementations, the functions/acts noted in the blocks may occur in a different order than as shown in the flowcharts. For example, two blocks shown in succession may be executed substantially concurrently, the blocks may be executed in the reverse order, or the blocks may not be executed in succession depending upon the functionality/acts involved.