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US 11,596,314 B2Granted
Methods, systems and apparatuses for detecting increased risk of sudden death
AssigneeLivaNova USA, Inc.
InventorShivkumar Sabesan
Life of this patent
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Abstract
Methods, systems, and apparatuses for detecting seizure events are disclosed, including a system for identification of an increased risk of a severe neurological event. The system may include an electroencephalogram (“EEG”) monitoring unit configured to collect EEG data from the patient during at least a postictal phase or one or more seizures and a processing unit configured to receive the EEG data from the EEG monitoring unit. The processing unit is configured to detect postictal EEG suppression from the EEG data and to identify the increased risk of the severe neurological event based on the detected postictal EEG suppression. Other embodiments are described and claimed.
Claims20
A system for identification of an increased risk of a severe neurological event, comprising a processing unit configured to:
- receive, from one or more electroencephalogram (EEG) sensors adapted to sense neurological activity of a patient, EEG data during at least a postictal phase of each of one or more seizures;
- receive at least one of:
- respiratory data during at least the postictal phase of each of the one or more seizures from one or more respiration sensors adapted to sense respiratory activity of the patient, or
- electrocardiogram (EKG) data during at least the postictal phase of each of the one or more seizures from one or more EKG sensors adapted to sense heart activity of the patient;
- detect, from the EEG data, at least one postictal EEG suppression period, wherein a postictal EEG suppression period is detected when the EEG data crosses an EEG threshold for at least a predetermined time period;
- detect, from the at least one of the respiratory data or the EKG data, that at least one of a respiration of the patient has fallen below a first threshold or an EKG measurement of the patient has fallen below a second threshold;
- identify the increased risk of the severe neurological event based on the detected at least one postictal suppression period and the at least one of the respiration falling below the first threshold or the EKG measurement falling below the second threshold;
- and
- provide, responsive to identifying the increased risk of the severe neurological event, at least one of an alert indicating the increased risk of the severe neurological event of the patient or a stimulation to the patient to assist in preventing the severe neurological event.
6 more elements
A method for identifying an increased risk of a severe neurological event, comprising:
- receiving, from one or more EEG sensors adapted to sense neurological activity of a patient, EEG data during at least a postictal phase of each of one or more seizures;
- receiving at least one of:
- respiratory data during at least the postictal phase of each of the one or more seizures from one or more respiration sensors adapted to sense respiratory activity of the patient;
- or
- EKG data during at least the postictal phase of each of the one or more seizures from one or more EKG sensors adapted to sense heart activity of the patient;
- detecting, from the EEG data, at least one postictal EEG suppression period, wherein a postictal EEG suppression period is detected when the EEG data crosses an EEG threshold for at least a predetermined time period;
- detecting, from the at least one of the respiratory data or the EKG data, that at least one of a respiration of the patient has fallen below a first threshold or an EKG measurement of the patient has fallen below a second threshold;
- identifying the increased risk of the severe neurological event based on the detected at least one postictal suppression period and the at least one of the respiration falling below the first threshold or the EKG measurement falling below the second threshold;
- and
- providing, responsive to identifying the increased risk of the severe neurological event, at least one of an alert indicating the increased risk of the severe neurological event of the patient or a stimulation to the patient to assist in preventing the severe neurological event.
7 more elements
A system for identification of an increased risk of a severe neurological event, comprising:
- an electroencephalogram (EEG) monitoring unit configured to receive EEG data generated by one or more EEG sensors adapted to sense neurological activity of a patient during at least a postictal phase of each of one or more seizures;
- at least one of:
- a respiration monitoring unit configured to receive respiration data generated by one or more respiration sensors adapted to sense respiratory activity of the patient during at least the postictal phase of each of the one or more seizures, or
- an electrocardiogram (EKG) monitoring unit configured to receive EKG data generated by one or more EKG sensors adapted to sense EKG activity of the patient during at least the postictal phase of each of the one or more seizures;
- and
- a processing unit configured to:
- receive the EEG data from the EEG monitoring unit;
- receive the at least one of the respiratory data from the respiratory monitoring unit or the EKG data from the EKG monitoring unit;
- detect, from the EEG data, at least one postictal EEG suppression period, wherein a postictal EEG suppression period is detected when the EEG data crosses an EEG threshold for at least a predetermined time period;
- detect, from the at least one of the respiratory data or the EKG data, that at least one of a respiration of the patient has fallen below a first threshold or an EKG measurement of the patient has fallen below a second threshold;
- identify the increased risk of the severe neurological event based on the detected at least one postictal suppression period and the at least one of the respiration falling below the first threshold or the EKG measurement falling below the second threshold;
- and
- provide, responsive to identifying the increased risk of the severe neurological event, at least one of an alert indicating the increased risk of the severe neurological event of the patient or a stimulation to the patient to assist in preventing the severe neurological event.
10 more elements
Dependencies are inferred from the claim text.