Methods of preparing highly charged polyethylenimine and compositions and uses thereof

Abstract

A method of preparing a disinfecting composition comprising charged polyethylenimine (PEI), the method comprising adding a base to an aqueous solution comprising a linear PEI hydrochloride solution to provide a linear PEI salt solution with a pH between 9-11, adding a first organic acid to reduce the pH to less than 7, removing about 20% to 100% of the salt from the solution, and optionally adding water and/or a second organic acid to obtain the disinfecting composition with a pH of 2-7. The method can further comprise adding at least one metal salt to the disinfecting composition. The resulting disinfecting solution can be used to provide antimicrobial products with enhanced antimicrobial performance, reduced toxicity, and/or able to leave a persistent “kill-later” film.

Dependencies are inferred from the claim text.