Arrangement for mixing fluids in a capillary driven fluidic system
AssigneemiDiagnostics NV
InventorLei Zhang
Life of this patent
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Abstract
There is provided an arrangement (100) which allows for mixing a first fluid with a second fluid at a predetermined volume mixing ratio in a capillary driven fluidic system. The arrangement (100) allows filling an initially empty mixing chamber (110) with the first fluid. The arrangement then allows emptying a predetermined fraction of the first fluid from the mixing chamber (110) such as to form an empty space in the mixing chamber (110). The arrangement then allows filling the empty space of the mixing chamber (110) with the second fluid, thereby allowing a predetermined volume of the first fluid to mix with a predetermined volume of the second fluid over time.
Claims13
An arrangement in a capillary driven fluidic system for mixing a first fluid with a second fluid at a predetermined volume mixing ratio, the arrangement comprising:
- a mixing chamber including a main chamber and one or more inner chambers, said main chamber and each of the one or more inner chambers being separated by a respective structure each including at least one opening which allows for fluid communication between the main and the one or more inner chambers and which, during use, is arranged to generate a capillary pressure (CP2) in the at least one opening which is larger than a capillary pressure (CP3) in the main chamber,
- wherein the mixing chamber extends in a longitudinal direction (D) and the main chamber extends in said longitudinal direction (D) along a full length of the mixing chamber,
- and wherein the mixing chamber is arranged to receive a first fluid so as to fill the main chamber and the one or more inner chambers, via the respective at least one opening, with the first fluid,
- a capillary pump arranged to draw fluid from the main chamber after the main chamber and the one or more inner chambers of the mixing chamber have been filled with the first fluid, wherein the capillary pump is arranged to operate at a capillary pressure (CP1) which is between the capillary pressure (CP3) of the main chamber and the capillary pressure (CP2) in the at least one opening of each respective structure such that the main chamber but not the one or more inner chambers is emptied of the first fluid, and
- wherein the mixing chamber is arranged to receive a second fluid so as to fill the main chamber with the second fluid after the main chamber has been emptied of the first fluid, such that the first fluid in the one or more inner chambers and the second fluid in the main chamber are enabled to mix through the at least one opening of the respective structure.
Dependencies are inferred from the claim text.