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US 11,590,273 B2Granted
Biological component collection system with pressure controlled filter and method
AssigneeTerumo Kabushiki Kaisha
InventorMasatsugu Igarashi
Life of this patent
Estimating the term…
Abstract
A centrifugal separation device of a blood component collection system, which is one form of a biological component collection system, performs a pressure release step of stopping a collection and returning pump at the end of a returning operation, and releasing a positive pressure inside a filter structural member, a clamp closure step of closing an inlet flow passage and an outlet flow passage of the filter structural member, and a collection operation starting step of starting a subsequent collection operation.
Claims20
A biological component collection system, comprising:
- a separation device having a centrifuge, and adapted to separate a biological component from a liquid containing at least one biological component;
- and
- a biological component collection device configured to be attachable to the separation device and having a flow path formed in an interior thereof;
- wherein the biological component collection device includes a collection line adapted to introduce the liquid containing the at least one biological component from a donor, a returning line adapted to return an uncollected biological component to the donor, and a filter structural member provided in the returning line, the collection line and the returning line communicating with each other via a branching member;
- the separation device includes a collection and returning pump disposed in a line between the centrifuge and the biological component collection device, and a clamp capable of opening and closing an inlet flow path and an outlet flow path of the filter structural member, and wherein a controller that controls the separation device drives the collection and returning pump to alternately carry out a collection operation of transferring the liquid containing the at least one biological component from the donor to the centrifuge via the collection line, and a returning operation for transferring an unnecessary biological component from the centrifuge to the donor via the returning line;
- and
- wherein the controller performs:
- a pressure release step of stopping the collection and returning pump at an end of the returning operation, and releasing a positive pressure inside the filter structural member;
- a clamp closure step of, after the pressure release step, controlling the clamp to close an inlet flow passage and an outlet flow passage of the filter structural member;
- and
- a collection operation starting step of, after the clamp closure step, starting a subsequent collection operation by driving the collection and returning pump.
8 more elements
The biological component collection system according to claim wherein the cassette comprises a cassette body made of a soft material.
A method of operating a biological component collection system, the biological component collection system comprising:
- a separation device having a centrifuge, and adapted to separate a biological component from a liquid containing at least one biological component;
- and
- a biological component collection device configured to be attachable to the separation device and having a flow path formed in an interior thereof;
- wherein the biological component collection device includes a collection line adapted to introduce the liquid containing the at least one biological component from a donor, a returning line adapted to return an uncollected biological component to the donor, and a filter structural member provided in the returning line, the collection line and the returning line communicating with each other via a branching member;
- the separation device includes a collection and returning pump disposed in a line between the centrifuge and the biological component collection device, and a clamp capable of opening and closing an inlet flow path and an outlet flow path of the filter structural member, and by driving the collection and returning pump, alternately carries out a collection operation of transferring the liquid containing the at least one biological component from the donor to the centrifuge via the collection line, and a returning operation for transferring an unnecessary biological component from the centrifuge to the donor via the returning line;
- and
- wherein the method of operating the biological component collection system includes:
- a pressure release step of stopping the collection and returning pump at an end of the returning operation, and releasing a positive pressure inside the filter structural member;
- a clamp closure step of, after the pressure release step, closing an inlet flow passage and an outlet flow passage of the filter structural member by the clamp;
- and
- a collection operation starting step of, after the clamp closure step, starting a subsequent collection operation by driving the collection and returning pump.
8 more elements
Dependencies are inferred from the claim text.