Sorbent for a dialysis device
AssigneeTemasek Polytechnic
InventorsChristian Gert Bluchel, Yanmei Wang, Kim Cheng Tan
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Abstract
There is provided a sorbent for removing metabolic waste products from a dialysis liquid, the sorbent comprising a layer of immobilized uremic toxin-treating enzyme particles intermixed with cation exchange particles.
Claims17
A fixed bed sorbent for removing metabolic waste products from a dialysis liquid, the sorbent comprising a primary layer of uremic toxin-treating enzyme particles covalently immobilized on a biocompatible material intermixed with cation exchange particles and anion exchange particles,
- wherein a pressure drop of the dialysis liquid across the primary layer is dependent on the size of said cation exchange particles;
- wherein said uremic toxin-treating enzyme particles and said cation exchange particles are, when in use, in direct contact with the dialysis liquid;
- and
- wherein the anion exchange particles and cation exchange particles are selected to create pH buffering conditions when in direct contact with the dialysis liquid.
A fixed bed sorbent for removing metabolic waste products from a dialysis liquid, the sorbent comprising a layer of uremic toxin-treating enzyme particles covalently immobilized on a biocompatible material intermixed with cation exchange particles having an average particle size in the range of 50 microns to 200 microns and anion exchange particles;
- wherein said uremic toxin-treating enzyme particles and said cation exchange particles are, when in use, in direct contact with the dialysis liquid;
- and
- wherein the anion exchange particles and cation exchange particles are selected to create pH buffering conditions when in direct contact with the dialysis liquid.
Dependencies are inferred from the claim text.