Formulation
AssigneeGlaxosmithkline Biologicals SA
InventorsErwan Bourles, Olivier Despas, Delphine Guillaume, Frederic Mathot, Mathieu Vasselle
Life of this patent
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Abstract
The present invention relates to the formulation of adenoviral vectors in sorbitol containing compositions in combination with a further amorphous sugar, its formulation as well as a method for obtaining a dried composition.
Claims18
A composition comprising a recombinant simian adenoviral vector, sorbitol, an amorphous sugar and NaCl, wherein the amorphous sugar is trehalose, the ratio of sorbitol to trehalose is 4/14 to 3/18 and the concentration of the NaCl is 2.5 mM to 7.5 mM the sorbitol is present in an amount of 3-4% (w/v) and the trehalose is present in an amount of 14-18% (w/v).
Dependencies are inferred from the claim text.