Cancer immunotherapy using virus particles
AssigneeCase Western Reserve University
InventorsNicole F. Steinmetz, Karin L. Lee
Life of this patent
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Abstract
A method of treating cancer in a subject in need thereof includes administering in situ to the cancer a therapeutically effective amount of a virus or virus-like particle.
Claims20
A method of treating cancer in a subject in need thereof, comprising administering directly to the cancer a therapeutically effective amount of an in situ vaccine, the in situ vaccine including at least one of potato virus X (PVX) or PVX virus-like particles wherein the PVX or PVX virus-like particles are not used as a vehicle for drug or antigen delivery, and wherein the subject is a non-human animal.
A method of treating cancer in a subject in need thereof, comprising administering to the subject therapeutically effective amounts of an anti-cancer agent and an in situ vaccine, wherein the in situ vaccine includes at least one of potato virus X (PVX) or PVX virus-like particles that are administered directly to the cancer, wherein the PVX or PVX virus-like particles are not used as a vehicle for drug or antigen delivery, and wherein the subject is a non-human animal.
Dependencies are inferred from the claim text.