Pharmaceutical paste formulations for site specific application

A pharmaceutical formulation comprising:

• sucralfate, as an active pharmaceutical ingredient, in a concentration ranging from about 8% w/w to about 12% w/w;
• malic acid, as an API solubilizer, in a concentration ranging from about 4.8% w/w to about 5.2% w/w;
• calcium carbonate, as a cross-linking agent, in a concentration ranging from about 2.4% w/w to about 2.6% w/w;
• calcium sulfate dihydrate, as a consistency improver, in a concentration ranging from about 0.05% w/w to about 1.5% w/w;
• xanthan gum, as a rheology modifier, in a concentration ranging from about 0.1% w/w to about 1.0% w/w;
• and
• propylene glycol, as a humectant, in a concentration ranging from about 2% w/w to about 10% w/w, wherein said pharmaceutical formulation is capable of being:
• packaged in a squeezable tube fitted with a site-specific applicator having an inner nozzle diameter of 0.61 mm;
• stored in said squeezable tube for a period of time of 2-years;
• and
• expelled from the squeezable tube through the site-specific applicator throughout said period of time.