Compositions and methods for treating acne vulgaris
AssigneeDermala, Inc.
InventorsLada Rasochova, Michelle Kem
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Abstract
Disclosed are compositions, methods of treatment using the compositions and methods of preparing the compositions for the treatment of acne vulgaris. The compositions include succinic acid and an API selected from the group consisting of salicylic acid, azelaic acid, picolinic acid, benzoyl peroxide, antibiotic, retinoid and combinations thereof in a pharmaceutically acceptable preparation. The compositions that include the combination of succinic acid and another API produce improved efficacy in treating acne vulgaris.
Claims16
A method of killing a Propionibacterium acnes (P. acnes) that is resistant to an antibiotic, the method comprising treating the P. acnes with a composition comprising a combination of salicylic acid and succinic acid present in a 1:2 ratio to produce a synergistic effect in treating acne vulgaris,
- wherein the P. acnes is resistant to erythromycin, clindamycin, minocycline, doxycycline, or any combination thereof.
Dependencies are inferred from the claim text.