Ascorbate in the prevention of statin induced vascular calcification
OwnerMatthias Rath, Vadim Ivanov +1inventors
InventorsMatthias Rath, Vadim Ivanov, Aleksandra Niedzwiecki
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Abstract
A method of treating or preventing vascular calcification in a patient by administering L-ascorbic acid or ascorbate to the patient and a pharmaceutical composition containing at least one statin and L-ascorbic acid or ascorbate in a dosage form that allows for the concomitant administering of the at least one statin and L-ascorbic acid or ascorbate to a patient.
Claims20
A method of treating or preventing vascular calcification in a patient by administering an effective amount of L-ascorbic acid or ascorbate to the patient,
- wherein the patient is concomitantly treated with at least one statin,
- wherein a daily dosage form consisting of a pharmaceutical composition consisting of at least one statin, L-ascorbic acid or ascorbate, vitamin B12, vitamin B5, vitamin B1, vitamin B2, vitamin B6, vitamin B7, vitamin B9, vitamin E, and optionally niacin and/or coenzyme Q10 is administered to the patient,
- wherein the amount of the L-ascorbic acid or ascorbate is from 100 mg to 10 g and the amount of the at least one statin is from 5 mg to 100 mg.
A method of treating or preventing vascular calcification in a patient treated with statins by administering an effective amount of L-ascorbic acid or ascorbate to the patient,
- wherein the patient is concomitantly treated with at least one statin,
- wherein a daily dosage form consisting of a pharmaceutical composition consisting of at least one statin, L-ascorbic acid or ascorbate, vitamin B12, vitamin B5, vitamin B1, vitamin B2, vitamin B6, vitamin B7, vitamin B9, vitamin E, and optionally niacin and/or coenzyme Q10 is administered to the patient,
- wherein the amount of the L-ascorbic acid or ascorbate is from 100 mg to 10 g and the amount of the at least one statin is from 5 mg to 100 mg.
Dependencies are inferred from the claim text.