Aqueous iron carbohydrate complexes, their production and medicaments containing them
AssigneeVifor (International) AG
InventorsPeter Geisser, Erik Philipp, Walter Richie
Life of this patent
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Abstract
A water soluble iron carbohydrate complex obtainable from an aqueous solution of iron (III) salt and an aqueous solution of the oxidation product of one or more maltodextrins using an aqueous hypochlorite solution at a pH-value within the alkaline range, where, when one maltodextrin is applied, its dextrose equivalent lies between 5 and 20, and when a mixture of several maltodextrins is applied, the dextrose equivalent of the mixture lies between 5 and 20 and the dextrose equivalent of each individual maltodextrin contained in the mixture lies between 2 and 40, process for its production and a medicament for the treatment and prophylaxis of iron deficiency conditions.
Claims17
A composition comprising at least one iron (III) carbohydrate complex, said iron (III) carbohydrate complex comprising:
- an oxidized maltodextrin ligand, wherein in the formation of the oxidized maltodextrin ligand when one maltodextrin is applied prior to oxidation the dextrose equivalent lies between 5 and 20, and when a mixture of several maltodextrins is applied, the dextrose equivalent of the mixture lies between 5 and 20 and the dextrose equivalent of each individual maltodextrins contained in the mixture lies between 2 and 40, and
- wherein said iron (III) carbohydrate complex has:
- an iron content of 20% to 35% (weight/weight), expressed in relation to the total weight of said iron (III) carbohydrate complex and
- a weight average molecular weight ranging from 80 kDa to 400 kDa.
Dependencies are inferred from the claim text.