Back to results
US 11,589,921 B2Granted
Systems, apparatuses and methods for delivery of ablative energy to tissue
AssigneeBoston Scientific Scimed, Inc.
InventorRaju Viswanathan
Life of this patent
Estimating the term…
Abstract
A system includes a pulse waveform generator and an ablation device coupled to the pulse waveform generator. The ablation device includes at least one electrode configured for ablation pulse delivery to tissue during use. The pulse waveform generator is configured to deliver voltage pulses to the ablation device in the form of a pulsed waveform. The pulsed waveform can include multiple levels of hierarchy, and multiple sets of electrodes can be activated such that their pulsed delivery is interleaved with one another.
Claims28
A system, comprising:
- a pulse waveform generator operatively coupled to an ablation device, the pulse waveform generator configured to:
- select a plurality of electrode sets from a plurality of electrodes of the ablation device, each electrode set from the plurality of electrode sets including a first subset of electrodes configured as one or more anodes and a second subset of electrodes configured as one or more cathodes;
- generate voltage pulses in the form of pulsed waveforms, each pulsed waveform including:
- (a) a first level of a hierarchy of the pulsed waveform that includes a first set of pulses and a first time delay separating successive pulses of the first set of pulses;
- (b) a second level of the hierarchy of the pulsed waveform that includes a plurality of first sets of pulses as a second set of pulses and a second time delay separating successive first sets of pulses, the second time delay being greater than the first time delay;
- and
- (c) a third level of the hierarchy of the pulsed waveform that includes a plurality of second sets of pulses as a third set of pulses and a third time delay separating successive second sets of pulses, the third time delay being greater than the second time delay;
- and
- deliver the voltage pulses to the plurality of electrode sets according to a predefined sequence with at least one pulsed waveform being applied across the first and second subsets of electrodes of each electrode set from the plurality of electrode sets.
6 more elements
A method, comprising:
- selecting a plurality of electrode sets from a plurality of electrodes of an ablation device, each electrode set including a first subset of electrodes configured to be anodes and a second subset of electrodes configured to be cathodes;
- generating voltage pulses in the form of pulsed waveforms, each pulsed waveform including:
- (a) a first level of a hierarchy of the pulsed waveform that includes a first set of pulses and a first time delay separating successive pulses of the first set of pulses;
- (b) a second level of the hierarchy of the pulsed waveform that includes a plurality of first sets of pulses as a second set of pulses and a second time delay separating successive first sets of pulses, the second time delay being greater than the first time delay;
- and
- (c) a third level of the hierarchy of the pulsed waveform that includes a plurality of second sets of pulses as a third set of pulses and a third time delay separating successive second sets of pulses, the third time delay being greater than the second time delay;
- and
- delivering the voltage pulses to the plurality of electrode sets according to a predefined sequence with at least one pulsed waveform being applied across the first and second subsets of electrodes of each electrode set from the plurality of electrode sets.
5 more elements
A system, comprising:
- a pulse waveform generator operatively coupled to an ablation device, the pulse waveform generator configured to:
- select electrode sets from a plurality of electrodes of the ablation device, each electrode set from the plurality of electrode sets including a first subset of electrodes configured as one or more anodes and a second subset of electrodes configured as one or more cathodes;
- generate voltage pulses in the form of pulsed waveforms, each pulsed waveform including:
- (a) a first level of a hierarchy of the pulsed waveform that includes a first set of pulses and a first time delay separating successive pulses of the first set of pulses;
- and
- (b) a second level of the hierarchy of the pulsed waveform that includes a plurality of first sets of pulses as a second set of pulses and a second time delay separating successive first sets of pulses, the second time delay being greater than the first time delay;
- and
- deliver the voltage pulses to the plurality of electrode sets by:
- delivering the plurality of first sets of pulses of a first pulse waveform to a first electrode set from the plurality of electrode sets;
- and
- delivering, (1) subsequent to delivering each first set of pulses of the first pulse waveform and (2) during the second time delay separating that first set of pulses from a successive first set of pulses of the first pulse waveform, the first set of pulses of one or more additional pulse waveforms to one or more additional electrode sets from the plurality of electrode sets according to a predefined sequence, such that successive first sets of pulses delivered to the one or more additional electrode sets follow successive first sets of pulses delivered to the first electrode set.
8 more elements
A method, comprising:
- selecting a plurality of electrode sets from a plurality of electrodes of an ablation device, each electrode set including a first subset of electrodes configured to be anodes and a second subset of electrodes configured to be cathodes;
- generating voltage pulses in the form of pulsed waveforms, each pulsed waveform including:
- (a) a first level of a hierarchy of the pulsed waveform that includes a first set of pulses and a first time delay separating successive pulses of the first set of pulses;
- and
- (b) a second level of the hierarchy of the pulsed waveform that includes a plurality of first sets of pulses as a second set of pulses and a second time delay separating successive first sets of pulses, the second time delay being greater than the first time delay;
- and
- delivering the voltage pulses to the plurality of electrode sets by:
- delivering the plurality of first sets of pulses of a first pulse waveform to a first electrode set from the plurality of electrode sets;
- and
- delivering, (1) subsequent to delivering each first set of pulses of the first pulse waveform and (2) during the second time delay separating that first set of pulses from a successive first set of pulses of the first pulse waveform, the first set of pulses of one or more additional pulse waveforms to one or more additional electrode sets from the plurality of electrode sets according to a predefined sequence, such that successive first sets of pulses delivered to the one or more additional electrode sets follow successive first sets of pulses delivered to the first electrode set.
7 more elements
Dependencies are inferred from the claim text.