Occlusion detection by pressure measurement

A system for occlusion detection comprising:

• a sheath having a length and a sheath lumen extending through the length of the sheath;
• a delivery system comprising:
• a delivery catheter extending between a proximal end and a distal end;
• and
• a handle coupled to the proximal end of the delivery catheter;
• a medical tool coupled to a distal end of the delivery catheter configured to be inserted at a target cavity within a portion of an organ of a patient, the target cavity being a left atrial appendage, the medical tool comprising:
• a hub including a bore defining an axis;
• an occluder portion coupled to the hub, the occluder portion configured to be moved to an occluder non-deployed position with the occluder portion within a distal portion of the sheath, and the occluder portion configured to be moved to an occluder deployed position upon the sheath being moved proximally relative to the occluder portion;
• and
• an anchor portion extending between a first end and a second end, the anchor portion having tines configured to engage tissue, the first end being coupled to the handle, the second end being pivotably coupled to a distal end portion of the occluder portion, wherein, upon the occluder portion maintaining the occluder deployed position, the anchor portion is pivotable relative to the occluder portion between an anchor non-deployed position and an anchor deployed position;
• at least one pressure sensor configured to directly measure a pressure of a blood pool in the left atrial appendage while blood is being suctioned from inside the left atrial appendage;
• and
• at least one processor configured to process the pressure measurement acquired from the at least one pressure sensor, the processor also configured to compare the pressure acquired from the at least one pressure sensor to a baseline pressure measurement of a left atrial appendage to determine the presence or absence of an occlusion;
• wherein the medical tool is arranged for positioning at the left atrial appendage with the occluder portion maintained in the occluder deployed position and the anchor portion pivoted to the anchor deployed position such that occlusion is not established, and wherein the delivery catheter injects a fluid through the hub and into the left atrial appendage as the baseline pressure measurement.